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Thermo Fisher Scientific Factor 8 Polyclonal Antibody
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Thermo Fisher Scientific Factor 8 Polyclonal Antibody

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Factor VIII 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. Human, Mouse, Rabbit, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.

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Thermo Fisher Scientific BS-0434R Factor 8 Polyclonal Antibody 100 ul pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific Factor 8 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Immunohistochemistry (Paraffin) (IHC (P)) 1:300
Immunohistochemistry (Frozen) (IHC (F)) 1:100–1:500
Immunocytochemistry (ICC/IF) 1:100–1:500
ELISA 1:500–1:1,000

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rabbit, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen KLH conjugated synthetic peptide derived from rat factor VIII
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Protein A
Storage Buffer 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains 0.02% ProClin 300
Storage Conditions -20°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation. Factor VIII acts as a cofactor for factor IXa which, in the presence of Ca²⁺ and phospholipids, converts factor X to the activated form Xa.
This gene produces two alternatively spliced transcripts:

  • Transcript variant 1 (isoform a): Encodes a large glycoprotein circulating in plasma, associated noncovalently with von Willebrand factor.
  • Transcript variant 2 (isoform b): Encodes a smaller protein primarily consisting of the phospholipid-binding domain essential for coagulant activity.

Defects in this gene result in hemophilia A, a common recessive X-linked coagulation disorder.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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