
Thermo Fisher Scientific TrxR1 Recombinant Rabbit Monoclonal Antibody (ARC1106)
TrxR1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. Human, Mouse, Rat에 반응하며, HEK293 세포에서 발현되었습니다. 고순도 친화 크로마토그래피 정제 제품으로, -20°C에서 보관합니다.
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- MA535564
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:4,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1106 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–649 of human Thioredoxin reductase 1 (TXNRD1) (Q16881) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849464 |
Product Specific Information
Immunogen sequence:
MGCAEGKAVA AAAPTELQTK GKNGDGRRRS AKDHHPGKTL PENPAGFTST ATADSRALLQ AYIDGHSVVI FSRSTCTRCT EVKKLFKSLC VPYFVLELDQ TEDGRALEGT LSELAAETDL PVVFVKQRKI GGHGPTLKAY QEGRLQKLLK MNGPEDLPKS YDYDLIIIGG GSGGLAAAKE AAQYGKKVMV LDFVTPTPLG TRWGLGGTCV NVGCIPKKLM HQAALLGQAL QDSRNYGWKV EETVKHDWDR MIEAVQNHIG SLNWGYRVAL REKKVVYENA YGQFIGPHRI KATNNKGKEK IYSAERFLIA TGERPRYLGI PGDKEYCISS DDLFSLPYCP GKTLVVGASY VALECAGFLA GIGLDVTVMV RSILLRGFDQ DMANKIGEHM EEHGIKFIRQ FVPIKVEQIE AGTPGRLRVV AQSTNSEEII EGEYNTVMLA IGRDACTRKI GLETVGVKIN EKTGKIPVTD EEQTNVPYIY AIGDILEDKV ELTPVAIQAG RLLAQRLYAG STVKCDYENV PTTVFTPLEY GACGLSEEKA VEKFGEENIE VYHSYFWPLE WTIPSRDNNK CYAKIICNTK DNERVVGFHV LGPNAGEVTQ GFAAALKCGL TKKQLDSTIG IHPVCAEVFT TLSVTKRSGA SILQAGCUG
Target Information
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. The protein reduces thioredoxins and other substrates, playing a role in selenium metabolism and protection against oxidative stress. The enzyme functions as a homodimer using FAD as a cofactor, with each subunit containing a selenocysteine residue essential for catalytic activity. The selenocysteine is encoded by a UGA codon, recognized as Sec through the SECIS element in the 3' UTR. Alternative splicing results in multiple transcript variants encoding identical or distinct isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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