
Thermo Fisher Scientific SMC1 Recombinant Rabbit Monoclonal Antibody (ARC1095)
SMC1 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot, ICC/IF, ELISA에 적합하며 인간 및 생쥐 시료 반응성. 고순도 친화 크로마토그래피 정제, 안정적 PBS/glycerol 저장용액 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1095 |
| Immunogen | Synthetic peptide corresponding to amino acids 1134–1233 of human SMC1 (UniProt ID: Q14683) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849458 |
Product Specific Information
Immunogen sequence:
TVAALALLFA IHSYKPAPFF VLDEIDAALD NTNIGKVANY IKEQSTCNFQ AIVISLKEEF YTKAESLIGV YPEQGDCVIS KVLTFDLTKY PDANPNPNEQ
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins are essential for various nuclear events requiring structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex essential for metaphase progression and sister chromatid cohesion.
Mutations in the SMC1 gene can cause Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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