Thermo Fisher Scientific eIF4A1 Recombinant Rabbit Monoclonal Antibody (ARC0636)
Thermo Fisher Scientific의 eIF4A1 재조합 토끼 단일클론 항체(ARC0636)는 Western blot, ICC/IF, IP에 적합한 고품질 연구용 항체입니다. HEK293 세포에서 발현된 비결합형 액상 항체로, 인간 eIF4A1(1-100 aa)에 특이적으로 반응합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0636 |
| Immunogen | A synthetic peptide corresponding to amino acids 1–100 of human eIF4A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.26 mg/mL |
| Storage Conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849039 |
Target Information
eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family.
It contains one helicase ATP-binding domain and a helicase C-terminal domain.
eIF4A2, a subunit of the eIF4F complex, acts as a protein-synthesis initiation factor and plays an important role in the binding of mRNA to the 43S pre-initiation complex of ribosomes.
Human eIF4A2 interacts with the NS5B protein of Hepatitis C virus (HCV) and facilitates genomic RNA synthesis by unwinding the secondary structure of the HCV genome.
It is ubiquitously expressed in most normal tissues, but in variable amounts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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