Thermo Fisher Scientific LUM Recombinant Rabbit Monoclonal Antibody (ARC0637)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0637

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 212-338 of human Lumican (LUM) (NP_0023361) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LUM,uniProtId:P51884-1,ncbiNodeId:9606,antigenRange:212-338,antigenLength:338,antigenImageFileName:MA5-35135_LUM_P51884-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35135_LUM_P51884-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.25 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849040

Product Specific Information

Immunogen sequence: LDNNKISNIP DEYFKRFNAL QYLRLSHNEL ADSGIPGNSF NVSSLVELDL SYNKLKNIPT VNENLENYYL EVNQLEKFDI KSFCKILGPL SYSKIKHLRL DGNRISETSL PPDMYECLRV ANEVTLN

Target Information

LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.