Thermo Fisher Scientific Caspase 3 Recombinant Superclonal Antibody (22HCLC)

Applications

Western Blot (WB)

• Tested Dilution: 1:100–1:1,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:1,000

Miscellaneous (PubMed)

• Publications: View 1 publication

Product Specifications

Product Specific Information

Recombinant rabbit Superclonal™ antibodies are composed of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
They recognize multiple epitopes on the target, providing higher detection sensitivity for low-abundance proteins.
Each lot contains a defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability.
Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. Product and performance remain unchanged.

Target Information

The Caspase 3 gene encodes a cysteine-aspartic acid protease involved in apoptosis.
Sequential activation of caspases drives cell death processes. Caspase 3 cleaves and activates caspases 6, 7, and 9, and is itself processed by caspases 8, 9, and 10.
It plays a key role in neuronal death associated with Alzheimer’s disease by cleaving amyloid-beta precursor protein.
Alternative splicing produces two transcript variants encoding the same protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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