Thermo Fisher Scientific OCRL Polyclonal Antibody
Thermo Fisher Scientific의 OCRL Polyclonal Antibody는 인간 및 생쥐 시료에서 OCRL 단백질을 검출하는 토끼 폴리클로날 항체입니다. Western blot과 IHC(P) 실험에 적합하며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific OCRL Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OCRL (Accession Q01968), corresponding to amino acid residues Q752–V802 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | –20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852523 |
Product Specific Information
This antibody detects endogenous levels of total OCRL.
Target Information
The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, generating second messengers in response to extracellular signals. OCRL1 is a type II 5-phosphatase mutated in the oculocerebrorenal syndrome of Lowe (OCRL), a rare X-linked disorder characterized by congenital cataracts, mental retardation, muscular hypotonia, and renal tubular dysfunction. OCRL1 has high affinity for phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate, and inositol 1,3,4,5-tetrakisphosphate as substrates. It is localized to the Golgi complex and is thought to be part of the trans-Golgi network (TGN), suggesting a role in protein sorting and trafficking within the cell.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.