Thermo Fisher Scientific OTUB1 Polyclonal Antibody
OTUB1 단백질을 인식하는 Thermo Fisher Scientific의 산양 유래 polyclonal 항체. Western blot에 최적화되어 있으며, 인간, 마우스, 랫트 등과 교차 반응 가능. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS 버퍼에 0.5% BSA와 0.02% sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific OTUB1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.03–0.1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (YKEYAEDDNIYQQK) corresponding to the internal amino acids of OTUB1 (aa 58–72) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10979709 |
Product Specific Information
- Predicted to react with bovine, human, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
OTUB1 is a member of the OTU superfamily of predicted cysteine proteases. It encodes a highly specific ubiquitin iso-peptidase that cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates.
It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.
OTUB1 may function in specific ubiquitin-dependent pathways by providing an editing function for polyubiquitin chain growth.
Alternative splicing results in multiple transcript variants.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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