Thermo Fisher Scientific RAMP1 Polyclonal Antibody
RAMP1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Rat에 반응하며 Western blot에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DYQSKRTEGIV) corresponding to the C-terminus amino acids of Ramp1 (aa 144–148) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10984135 |
Product Specific Information
- Predicted to react with human and mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs).
RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus.
They are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane.
CRLR can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which RAMP family members are expressed.
In the presence of RAMP1, CRLR functions as a CGRP receptor.
RAMP1 is involved in terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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