Thermo Fisher Scientific NCoR1 Monoclonal Antibody (A6H12)
NCoR1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. Recombinant NCoR1(aa 251-450) 항원으로 제작. 단백질 G 정제, 2 mg/mL 농도, PBS 기반 버퍼에 보존. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:600
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A6H12 |
| Immunogen | Recombinant protein within human Nuclear Receptor Corepressor (NCoR1) aa 251–450 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931438 |
Target Information
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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