Thermo Fisher Scientific ABHD3 Monoclonal Antibody (A5D4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Plant

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

A5D4

Immunogen

Recombinant full length protein within Camellia.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein G

Storage buffer

TBS, pH 7.4, with 0.2% BSA, 50% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2931443

Target Information

The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer`s disease, obesity and blood clotting disorders. The α/β hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostlyuncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD3 is a 409 amino acid single-pass type II membrane protein. ABHD4 is involved in an alternative synthesis pathway of NAE (N-acyl ethanolamine). Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.