Thermo Fisher Scientific LKB1 Polyclonal Antibody
인간 LKB1/STK11 단백질을 인식하는 Rabbit Polyclonal 항체입니다. Western blot 및 ELISA에 사용 가능하며, PBS 용액 형태로 제공됩니다. 종양 억제 단백질 연구 및 AMPK 관련 신호전달 연구에 적합합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human LKB1/STK11 serine/threonine kinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1087557 |
Product Specific Information
A suggested positive control for this product is lung or uterus lysate.
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11) is a tumor suppressor belonging to the serine/threonine kinase family.
LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
It is present in both the cytoplasm and nucleus and translocates to mitochondria during apoptosis.
LKB1 functions as a master upstream protein kinase, regulating AMPK-related kinases as well as AMPK.
Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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