Thermo Fisher Scientific PPAPDC2 Polyclonal Antibody
Thermo Fisher Scientific의 PPAPDC2 Polyclonal Antibody는 인간 PPAPDC2 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot 및 면역침강(IP)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/BSA buffer에 보관됩니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific PPAPDC2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400–1:800 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human phosphatidic acid phosphatase type 2 domain containing 2 (PPAPDC2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2237185 |
Product Specific Information
A suggested positive control for this product is testis lysate.
Target Information
PPAPDC2 is a phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), indicating an important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation.
PPAPDC2 displays diphosphate phosphatase activity with substrate preference for PSDP > FDP > phosphatidic acid. Its activity is independent of Mg²⁺ and has been identified in activated human neutrophil (PMN) extracts.
It is widely expressed in human tissues, and recent studies show PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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