Thermo Fisher Scientific PKC Polyclonal Antibody
PKC 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 인간, 마우스, 랫트 반응성. 세포질 내 PKC 검출에 적합.
- 카탈로그번호
- 500-9234
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to C-term of human PKC beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: SKBR-3 cells
- Cellular location: Cytoplasmic
Target Information
Protein Kinase C (PKC) is a multifunctional protein kinase that plays a critical regulatory role in a wide variety of cellular signaling processes. It is a ubiquitous calcium and phospholipid-dependent protein kinase.
At least 10 PKC isoforms are reported to exist, classified as conventional, novel, and atypical isoforms (Ohno and Nishizuka, 2002).
PKC is one of the three major protein kinases (including CaM Kinase II and PKA) that mediate cellular responses to second messengers.
It regulates numerous cellular functions including neurotransmitter synthesis and release, gene expression, ion channel function, and synaptic plasticity (Lu et al., 1999; Grosshans et al., 2002; Nishizuka, 1995).
The catalytic fragment of PKC (PKC-M) does not require Ca²⁺ or phosphatidylserine for its activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: 500-9234_PKC_Q05513-1_Rabbit.svg / 500-9234_PKC_Q05513-1_Rabbit_PDP.jpeg)
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