Thermo Fisher Scientific IL-6 Monoclonal Antibody (MQ2-13A5), APC, eBioscience

Thermo Fisher Scientific IL-6 Monoclonal Antibody (MQ2-13A5), APC, eBioscience™

Applications

• Intracellular staining
• Flow cytometry analysis

Tested Dilution

• 5 µL (0.06 µg)/test

Publications

• View 10 publications

Product Specifications

Available Formats

• Unconjugated
• Alexa Fluor 700
• eFluor 450
• FITC
• Functional Grade
• PE
• PE-Cyanine7
• PerCP-eFluor 710
• Request custom conjugation

Product Specific Information

The MQ2-13A5 antibody reacts with human interleukin-6 (IL-6), a 21–28 kDa cytokine secreted by various cell types.
This antibody is validated for intracellular staining followed by flow cytometric analysis.
Pre-titrated and tested using stimulated human peripheral blood cells at 5 µL (0.06 µg) per test.
A test is defined as the amount of antibody that stains a cell sample in a final volume of 100 µL.
Typical cell numbers range from 10⁵ to 10⁸ cells/test.
Excitation: 633–647 nm; Emission: 660 nm; Laser: Red Laser.
Filtered post-manufacturing through 0.2 µm filter.

Target Information

IL-6 encodes a cytokine involved in inflammation and B-cell maturation.
This protein acts as an endogenous pyrogen, inducing fever in autoimmune or infectious conditions.
It is mainly expressed at sites of acute and chronic inflammation, secreted into serum, and activates transcriptional inflammatory responses via IL-6 receptor alpha.
IL-6 is implicated in numerous inflammatory diseases, including diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi sarcoma, and rheumatoid arthritis.
Elevated IL-6 levels have also been observed in viral infections such as COVID-19 (SARS-CoV-2).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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