Thermo Fisher Scientific PHGDH Monoclonal Antibody (CL0555)
Thermo Fisher Scientific의 PHGDH 단일클론 항체(CL0555)는 인간 PHGDH 단백질을 특이적으로 인식합니다. Western blot, IHC, ICC/IF에 최적화되어 있으며, 고순도 Protein A 정제 및 안정적인 PBS/glycerol 저장 조건을 제공합니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL0555 |
| Immunogen | Recombinant protein corresponding to Human PHGDH (UniProt ID: O43175-1, antigen range: 193–306, antigen length: 533) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2786994 |
Product Specific Information
Immunogen sequence:
LEEIWPLCDF ITVHTPLLPS TTGLLNDNTF AQCKKGVRVV NCARGGIVDE GALLRALQSG QCAGAALDVF TEEPPRDRAL VDHENVISCP HLGASTKEAQ SRCGEEIAVQ FVDM
Target Information
PHGDH gene encodes the enzyme involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in families with congenital microcephaly, psychomotor retardation, and other symptoms. Multiple alternatively spliced transcript variants have been identified, though the full-length nature of most is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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