Thermo Fisher Scientific ERCC1 Monoclonal Antibody (CL1284)
ERCC1 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 단백질 A로 정제되었으며, PBS 기반의 안정한 액상 형태로 제공됩니다. 인간 ERCC1 단백질 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL1284 |
| Immunogen | Recombinant protein corresponding to Human ERCC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2786996 |
Product Specific Information
Immunogen sequence:
LADCTLILAW SPEEAGRYLE TYKAYEQKPA DLLMEKLEQD FVSRVTECLT TVKSVNKTDS QTLLTTFGSL EQLIAASRED LALCPGLGPQ KARRLFDVLH EPFLKVP
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair. It functions with SLX4 in the repair of interstrand cross-links (ICL) and participates in processing anaphase bridge-generating DNA structures, which can lead to cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks in conjunction with SLX4. (Source: Uniprot)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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