Thermo Fisher Scientific Acinus Polyclonal Antibody
Human 유래 Acinus 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. 냉장 또는 냉동 보관 가능. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to amino acids near the carboxy terminus of human AcinusL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151994 |
Product Specific Information
- In Western blot applications, this antibody detects a band at approximately 220 kDa.
- Suggested positive control: K562 cell lysate.
- PA5-19939 can be used with blocking peptide PEP-0064.
Target Information
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an inducer of chromatin condensation.
It is cleaved by caspase-3 and another unknown protease to generate a small active peptide, p17, which induces chromatin condensation in vitro when added to purified nuclei.
ACINUS also induces apoptotic chromatin condensation in cells and is ubiquitously expressed.
Three different spliced forms of Acinus have been identified in human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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