Thermo Fisher Scientific Acinus Polyclonal Antibody
Western blot과 Immunocytochemistry에 적합한 Rabbit Polyclonal Antibody. Human Acinus 단백질을 타겟으로 하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태, 1 mg/mL 농도, 냉장 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to amino acids 775–789 of human AcinusL, 48–62 of human AcinusS′, or 17–31 of human AcinusS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at −20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153762 |
Product Specific Information
- In Western blot applications, this antibody detects a band at approximately 220 kDa.
- Suggested positive control: K562 cell lysate.
- PA5-19940 can be used with blocking peptide PEP-0065.
Target Information
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an inducer of chromatin condensation.
It is cleaved by caspase-3 and an additional unknown protease, generating a small active peptide (p17) that causes chromatin condensation in vitro when added to purified nuclei.
ACINUS also induces apoptotic chromatin condensation in cells and is ubiquitously expressed.
Three different spliced forms of Acinus have been identified in human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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