Thermo Fisher Scientific Acinus Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:100

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A peptide corresponding to amino acids 775 to 789 of human AcinusL, 48 to 62 of human AcinusS prime, or 17 to 31 of human AcinusS if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Acinus,uniProtId:Q9UKV3-1,ncbiNodeId:9606,antigenRange:775-789,antigenLength:1341,antigenImageFileName:PA5-19940_Acinus_Q9UKV3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-19940_Acinus_Q9UKV3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11153762

Product Specific Information

In Western blot applications, this antibody detects a band at ~220kDa. A suggested positive control is K562 cell lysate.

PA5-19940 can be used with blocking peptide PEP-0065.

Target Information

ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.