Thermo Fisher Scientific CTNNA3 Polyclonal Antibody, MaxPab
CTNNA3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, Western blot 및 in situ PLA에 최적화되어 있습니다. 인간 및 생쥐 시료에 반응하며, PBS(pH 7.4) 용액 내 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제된 고품질 연구용 항체입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| in situ PLA (PLA) | 1:1,200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CTNNA3 (AAH65819.1, 1 a.a. ~ 516 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MSAETPITLN IDPQDLQVQT FTVEKLLEPL IIQVTTLVNC PQNPSSRKKG RSKRASVLLA SVEEATWNLL DKGEKIAQEA TVLKDELTAS LEEVRKESEA LKVSAERFTD DPCFLPKREA VVQAARALLA AVTRLLILAD MIDVMCLLQH VSAFQRTFES LKNVANKSDL QKTYQKLGKE LENLDYLAFK RQQDLKSPNQ RDEIAGARAS LKENSPLLHS ICSACLEHSD VASLKASKDT VCEEIQNALN VISNASQGIQ NMTTPPEPQA ATLGSALDEL ENLIVLNPLT VTEEEIRPSL EKRLEAIISG AALLADSSCT RDLHRERIIA ECNAIRQALQ DLLSEYMNNA GKKERSNTLN IALDNMCKKT RDLRRQLRKA IIDHVSDSFL DTTVPLLVLI EAAKNGREKE IKEYAAIFHE HTSRLVEVAN LACSMSTNED GIKIVKIAAN HLETLCPQII NAALALAARP KSQAVKNTME MYKRTWENHI HVLTEAVDDI TSIDDFLAVS GMFLFF
Target Information
Catenins are proteins that connect cadherin/beta-catenin cell adhesion complexes to the actin cytoskeleton. Although originally discovered in testis, alphaT-catenin is expressed in other tissues, with the highest levels observed in the heart. Immunohistochemical analysis shows human alphaT-catenin localization at intercalated discs of cardiomyocytes and in peritubular myoid cells of the testis. AlphaT-catenin can functionally restore cell-cell adhesion in colon cancer cells lacking alpha-catenins, indicating its role in specific muscle cell-cell contact formation. The encoded protein (~100 kDa) shares about 57% amino acid identity with other alpha-catenins. The 892_24D2S antibody against alphaT-catenin does not cross-react with alphaE- or alphaN-catenin in Western blot analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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