
Thermo Fisher Scientific CTNNA3 Polyclonal Antibody, MaxPab
CTNNA3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 랫트 반응성을 보입니다. Western blot에 최적화되어 있으며, 액상 형태로 PBS 버퍼에 보존됩니다. 연구용으로 세포 간 접착 관련 단백질 분석에 적합합니다.
- 카탈로그번호
- H00029119-B01P
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific CTNNA3 Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CTNNA3 (AAH65819.1, 1 a.a. ~ 516 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSAETPITLN IDPQDLQVQT FTVEKLLEPL IIQVTTLVNC PQNPSSRKKG RSKRASVLLA SVEEATWNLL DKGEKIAQEA TVLKDELTAS LEEVRKESEA LKVSAERFTD DPCFLPKREA VVQAARALLA AVTRLLILAD MIDVMCLLQH VSAFQRTFES LKNVANKSDL QKTYQKLGKE LENLDYLAFK RQQDLKSPNQ RDEIAGARAS LKENSPLLHS ICSACLEHSD VASLKASKDT VCEEIQNALN VISNASQGIQ NMTTPPEPQA ATLGSALDEL ENLIVLNPLT VTEEEIRPSL EKRLEAIISG AALLADSSCT RDLHRERIIA ECNAIRQALQ DLLSEYMNNA GKKERSNTLN IALDNMCKKT RDLRRQLRKA IIDHVSDSFL DTTVPLLVLI EAAKNGREKE IKEYAAIFHE HTSRLVEVAN LACSMSTNED GIKIVKIAAN HLETLCPQII NAALALAARP KSQAVKNTME MYKRTWENHI HVLTEAVDDI TSIDDFLAVS GMFLFF
Target Information
Catenins are proteins that connect cadherin/beta-catenin cell adhesion complexes to the actin cytoskeleton. Although originally discovered in testis, alphaT-catenin is expressed in other tissues, with the highest levels observed in heart.
Immunohistochemical analysis shows human alphaT-catenin localization at intercalated discs of cardiomyocytes and in peritubular myoid cells of testis.
AlphaT-catenin can functionally restore cell-cell adhesion in colon cancer cells lacking alpha-catenins, indicating its role in forming specific cell-cell contacts in muscle cells.
The encoded protein has a predicted size (~100 kDa) similar to other alpha-catenins with ~57% amino acid identity.
In transfected cells, alphaT-catenin interacts with alpha-catenin by coimmunoprecipitation.
The 892_24D2S antibody against alphaT-catenin does not cross-react with alphaE-catenin or alphaN-catenin in Western blot analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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