
Thermo Fisher Scientific TTF-1/NKX2.1 Recombinant Mouse Monoclonal Antibody (rNX2.1, 690)
Recombinant mouse monoclonal antibody recognizing TTF-1/NKX2.1 for IHC applications. High specificity to human, mouse, and rat. Purified via Protein A/G, supplied as liquid at 1 mg/mL. Ideal for research on thyroid transcription factors and morphogenesis.
- 카탈로그번호
- 7080-MSM4-P1ABX
- 판매단위
- pk
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Thermo Fisher Scientific TTF-1/NKX2.1 Recombinant Mouse Monoclonal Antibody (rNX2.1, 690)
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rNX2.1, 690 |
| Immunogen | Recombinant full-length human TTF-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates expression of thyroid-specific genes, as well as genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, neonatal respiratory distress, and may be linked to thyroid cancer. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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