Thermo Fisher Scientific UGT1A9 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: H1299, HeLa, HepG2, mouse liver
• Predicted reactivity: Mouse (90%), Rat (89%), Sheep (89%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules—such as steroids, bilirubin, hormones, and drugs—into water-soluble, excretable metabolites.
This gene is part of a complex locus encoding several UDP-glucuronosyltransferases. It includes thirteen alternate first exons followed by four common exons; nine of these can be spliced to produce proteins with different N-termini but identical C-termini. Each first exon encodes the substrate binding site and has its own promoter. The enzyme encoded by this gene is active on phenols.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.