Thermo Fisher Scientific PBK Monoclonal Antibody (2C8)
인간 PBK 단백질을 인식하는 Mouse IgG2b 단클론 항체로 다양한 응용(WB, IHC, ICC, Flow, ELISA)에 적합. 비결합형 액상 형태이며 4°C 단기, -20°C 장기보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C8 |
| Immunogen | Purified recombinant fragment of human PBK expressed in E. Coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2538615 |
Product Specific Information
MA5-17144 targets PBK in indirect ELISA, FACS, ICC, IHC, IF, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human PBK expressed in E. coli.
MA5-17144 detects PBK with a predicted molecular weight of approximately 36 kDa.
Target Information
PBK (TOPK) is a serine/threonine kinase related to dual-specific mitogen-activated protein kinase (MAPKK).
This kinase is up-regulated in various hematological malignancies, participates in activating lymphoid cells, and supports testicular function (spermatogenesis).
Mitotic phosphorylation is required for catalytic activity, suggesting its role in lymphoid cell activation and spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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