Thermo Fisher Scientific PDE1B Monoclonal Antibody (5C4A3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000

-

Flow Cytometry (Flow)

1:200-1:400

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

5C4A3

Immunogen

Purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDE1B,uniProtId:Q01064-1,ncbiNodeId:9606,antigenRange:370-536,antigenLength:536,antigenImageFileName:MA5-17147_PDE1B_Q01064-1_House_mouse.svg,antigenImageFileNamePDP:MA5-17147_PDE1B_Q01064-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2538618

Product Specific Information

MA5-17147 targets PDE1B in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human and Rat samples.

The MA5-17147 immunogen is purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli.

MA5-17147 detects PDE1B which has a predicted molecular weight of approximately 61.4kDa.

Target Information

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.