
Thermo Fisher Scientific Interferon alpha-1 (IFNA1) Monoclonal Antibody (2-48)
인간 IFN alpha-1을 인식하는 mouse monoclonal 항체로, WB, IHC(F), ICC/IF, Flow Cytometry에 사용 가능. Protein A/G로 정제된 액상형 항체이며, 4°C 보관. 연구용으로 바이러스 감염 관련 면역 반응 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2-48 |
| Immunogen | Purified recombinant human IFN-alpha1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interferon alpha (IFN alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins found only in vertebrates. Interaction of IFN alpha with its receptor triggers multiple signaling pathways involved in innate immune responses against viral infections. In humans, the IFN alpha gene is located on chromosome 9. Type I interferons include 14 alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules exist across many species, including mammals, birds, reptiles, and fish. IFN alpha is mainly produced by plasmacytoid dendritic cells and plays a crucial role in antiviral innate immunity and modulation of adaptive immune responses. Dysregulation of IFN alpha is associated with diseases such as Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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