Thermo Fisher Scientific KV2.2 (KCNB2) Polyclonal Antibody
Rabbit polyclonal antibody against KV2.2 (KCNB2), suitable for WB, IHC, ICC/IF, and IP. Recognizes rat Kv2.2 residues 859–873. Lyophilized form, 0.8 mg/mL concentration, stored at -20°C. For research use only.
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- PA577634
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide CRQDIYQAVGEVKKD, corresponding to amino acid residues 859–873 of rat Kv2.2 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736065 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
Kcnb2 (Kv2.2) encodes a voltage-gated K⁺ channel that plays a key role in neuronal membrane excitability.
Differences in K⁺ channel expression influence action potential waveform and firing patterns across neuronal types.
Kv2.1 and Kv2.2 are expressed in neuronal somata, dendrites, and various non-neuronal cells (pancreatic islets, alveolar cells, cardiac myocytes).
Kcnb2 mediates voltage-dependent potassium ion permeability of excitable membranes, opening or closing in response to membrane potential changes.
Diseases associated with KCNB2 include Brugada Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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