Thermo Fisher Scientific KVbeta2 (KCNAB2) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:400

-

Immunohistochemistry (Frozen) (IHC (F))

Assay-Dependent

-

Immunocytochemistry (ICC/IF)

1:200

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide SPGMIYSTRYGSPKR(C), corresponding to amino acid residues 20-34 of rat Kv beta2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KVbeta2 (KCNAB2),uniProtId:P62483-1,ncbiNodeId:10114,antigenRange:20-34,antigenLength:367,antigenImageFileName:PA5-77631_KVbeta2_KCNAB2_P62483-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77631_KVbeta2_KCNAB2_P62483-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2736074

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

Kcnab2 is a voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The alpha-subunits contain a single pore-forming region and combine to form tetramers. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. The diverse functions of potassium channels include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). Kcnab2 is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. Alternative splicing of the Kcnab2 gene results in multiple transcript variants encoding distinct isoforms. Diseases associated with KCNAB2 include Chromosome 1P36 Deletion Syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.