Thermo Fisher Scientific VMP1 Polyclonal Antibody
VMP1 단백질을 검출하기 위한 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 면역세포화학(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 용액 형태로 제공되며 -20°C에 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from the C-terminal of Human VMP1 (aa 391–402) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2736786 |
Product Specific Information
A 1:1,000 dilution of PA5-77784 was sufficient for detection of VMP1 in 15 µg of Human 293T cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 46 kDa.
Target Information
VMP1 is a stress-induced transmembrane protein that promotes formation of intracellular vacuoles and may be involved in cytoplasmic vacuolization during early acute pancreatitis. It co-localizes with LC3, a marker of autophagosomes, and interacts with beclin-1 through the VMP1-Atg domain, which is essential for autophagosome formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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