Thermo Fisher Scientific VEGFR2/CD309/Flk-1/KDR3 (Hemangioblast Marker) Monoclonal Antibody (KDR721)
VEGFR2/CD309/Flk-1/KDR3 단일클론 항체로 인간 시료에 반응하며 혈관내피 성장인자 수용체 연구에 적합. ICC/IF, Flow Cytometry, Functional Assay에 사용 가능. 단백질 A/G 정제, 액상 형태, 4°C 보관. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–2 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/10^6 cells
Functional Assay (Functional)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KDR721 |
| Immunogen | Recombinant human VEGF-R2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase that binds vascular endothelial growth factor (VEGF) with high affinity in vitro. It is expressed early in development by endothelial cell precursors. FLK1 (VEGF Receptor 2) encodes one of the two receptors of VEGF, known as kinase insert domain receptor. The signaling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, and T-cell protein tyrosine phosphatase. Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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