Thermo Fisher Scientific FGG Monoclonal Antibody (OTI4D3), TrueMAB
FGG 단백질을 인식하는 마우스 단클론 항체로 Western blot과 IHC(P)에서 검증됨. 비결합형, 동결건조 형태로 제공되며 PBS buffer에 8% 트레할로스 포함. 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D3 |
| Immunogen | Full length human recombinant protein of human FGG produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The FGG gene encodes the gamma component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains.
After vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the primary component of blood clots.
Cleavage products of fibrinogen and fibrin also regulate cell adhesion, spreading, vasoconstriction, and chemotactic activities, and act as mitogens for several cell types.
Mutations in this gene are associated with disorders such as dysfibrinogenemia, hypofibrinogenemia, and thrombophilia.
Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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