Thermo Fisher Scientific IL-2 Monoclonal Antibody (JES6-IAI2)
마우스 IL-2에 반응하는 Rat IgG1 단클론 항체로, ELISA 및 중화시험에 적합합니다. E. coli 유래 재조합 IL-2로 면역화되었으며, 단백질 A/G로 정제된 동결건조 형태입니다. 연구용으로만 사용되며, 높은 순도와 낮은 엔도톡신 수준을 제공합니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 0.1–0.4 µg/mL (Detection), 2–8 µg/mL (Capture)
- View 1 publication
Neutralization (Neu)
- Tested Dilution: 0.125–0.75 µg/mL
Inhibition Assays (IA)
- Tested Dilution: Not specified
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | JES6-IAI2 |
| Immunogen | E. coli-derived recombinant mouse IL-2 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609747 |
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism for precise gene expression.
Disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease, indicating its essential role in immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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