Thermo Fisher Scientific IL1RA Monoclonal Antibody (10309)

Applications

Tested Dilution

Publications

ELISA (ELISA)

0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture)

-

Neutralization (Neu)

10-20 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

10309

Immunogen

E. coli-derived recombinant human IL-1ra/IL-1F3 Arg26-Glu177 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL1RA,uniProtId:P18510-1,ncbiNodeId:9606,antigenRange:26-177,antigenLength:177,antigenImageFileName:MA5-23802_IL1RA_P18510-1_House_mouse.svg,antigenImageFileNamePDP:MA5-23802_IL1RA_P18510-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2609295

Product Specific Information

In ELISAs, this antibody shows less than 0.2% cross-reactivity with recombinant mouse (rm) IL-1ra and no cross-reactivity with rhIL-1 alpha, rpIL-1 alpha, rmIL-1 alpha, rrIL-1 alpha, rhIL-1 beta, rpIL-1 beta, rmIL-1 beta, rrIL-1 beta, rhIL-1 RI, or rhIL-1 RII.

Reconstitute at 0.5 mg/mL in sterile PBS.

Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.