Thermo Fisher Scientific HIF3A Polyclonal Antibody, DyLight 650
DyLight 650 형광 표지된 HIF3A 폴리클로날 항체로 웨스턴 블롯에 적합. 인간 HIF-3α N-말단을 면역원으로 사용. 651/673 nm 최대 흡수/방출 특성. 4°C 암소 보관, 연구용 전용.
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Thermo Fisher Scientific HIF3A Polyclonal Antibody, DyLight 650
Applications
- Western Blot (WB)
Tested Dilution: 1:100–1:200
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Bacterially expressed human HIF-3 alpha (N-terminus) |
| Conjugate | DyLight™ 650 |
| Excitation / Emission Max | 651 / 673 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C, store in dark |
| Shipping conditions | Wet ice |
| RRID | AB_11157625 |
Product Specific Information
- Suggested positive control: reticulocyte lysate.
Target Information
Cell growth and viability are compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1α, HIF-1β (Arnt 1), EPAS-1 (HIF-2α), and HIF-3α, induce glycolysis, erythropoiesis, and angiogenesis to restore oxygen homeostasis.
These factors belong to the Per-Arnt-Sim (PAS) domain transcription factor family.
Under hypoxic conditions, HIF-1α is upregulated and forms a heterodimer with Arnt 1, creating the HIF-1 complex that binds to the hypoxia responsive element (HRE) of target genes, activating transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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