Thermo Fisher Scientific HIF3A Polyclonal Antibody, HRP
HIF-3α 단백질을 인식하는 HRP 결합 폴리클로날 항체입니다. Western blot에 적합하며, 제안된 희석 배수는 1:100~1:200입니다. 저산소 반응 관련 연구에 활용되며, 4°C 암소 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA522717
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:100–1:200
- Suggested positive control: Reticulocyte lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Bacterially expressed human HIF-3 alpha (N-terminus) |
| Conjugate | HRP |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C, store in dark |
| Shipping conditions | Wet ice |
| RRID | AB_11152020 |
Target Information
Cell growth and viability are compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1α, HIF-1β (Arnt 1), EPAS-1 (HIF-2α), and HIF-3α, regulate glycolysis, erythropoiesis, and angiogenesis to restore oxygen homeostasis. These factors belong to the Per-Arnt-Sim (PAS) domain transcription factor family. Under hypoxic conditions, HIF-1α is upregulated and forms a heterodimer with Arnt 1 to create the HIF-1 complex, which binds to the hypoxia response element (HRE) of target genes to activate transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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