Thermo Fisher Scientific Human IL-13 Recombinant Protein, eBioscience

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-Dependent

-

Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

Human IL-13 recombinant protein contains 114 amino acids

Molecular weight

12.5 kDa

Class

Recombinant

Type

Protein

Purity

>95%

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Storage buffer

PBS, pH 7.2

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Description: Interleukin-13 is an immunoregulatory protein produced by activated T-lymphocytes. The biological activities of IL-13 include the stimulation of B cell proliferation and immunoglobulins production. Recombinant human IL-13 is a 12.5 kDa protein containing 114 amino acid residues.

Purity: >95%.

Molecular Weight: 12.5 kDa.

Target Information

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.