Thermo Fisher Scientific ALDH3A2 Polyclonal Antibody
Rabbit polyclonal antibody against human ALDH3A2. Validated for WB and ICC/IF. High specificity and cross-species homology. Supplied as liquid, affinity purified, 0.5 mg/mL in PBS with sucrose and sodium azide. For research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human ALDH3A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688624 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Target Information
Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. These enzymes play a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder characterized by ichthyosis, mental retardation, and spastic diplegia. The pathogenesis is thought to result from abnormal lipid accumulation, formation of aldehyde Schiff base adducts, or defective eicosanoid metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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