Thermo Fisher Scientific CD79a Recombinant Rabbit Monoclonal Antibody (IGA, 1688R)
CD79a 단백질을 표적하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot, IHC, ICC/IF, Flow cytometry에 적합하며, 인간, 마우스, 랫트 시료에 반응합니다. Protein A로 정제된 액상 항체로, 보존제가 포함되어 있지 않습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | IGA, 1688R |
| Immunogen | A synthetic peptide corresponding to aa 202–216 (GTYQDVGSLNIADVQ) of human CD79a protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CD79a is a disulfide-linked heterodimer that includes the B29 (CD79b) polypeptide. It functions as part of the B lymphocyte antigen receptor complex, associating with Ig-alpha and Ig-beta, which are essential for B-cell receptor expression and signaling. CD79a expression begins at the pre-B cell stage and continues through the plasma cell stage, where it is found intracellularly. It is present in most acute leukemias of precursor B-cell type, B-cell lines, lymphomas, and some myelomas, but absent in myeloid or T-cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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