
Thermo Fisher Scientific Aquaporin 1 Recombinant Rabbit Monoclonal Antibody (JM10-98)
Aquaporin 1 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션. 단기 4°C, 장기 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2000–1:5000 | – |
| Immunohistochemistry (IHC) | – | 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:1000 | – |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM10-98 |
| Immunogen | Synthetic peptide within Human AQP1 aa 245–269 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809870 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal clones for production.
Advantages include:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
Aquaporin 1 (AQP1) is a 28 kDa integral membrane protein originally identified in red blood cells and renal proximal tubules. It is also expressed in the choroid plexus and other tissues.
AQP1 forms a water-specific channel, providing high water permeability to plasma membranes of red cells and kidney proximal tubules, facilitating osmotically driven water movement.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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