Thermo Fisher Scientific PLXND1 Polyclonal Antibody
PLXND1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에서 반응합니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. Plexin D1 단백질의 세포 신호 조절 및 혈관 발달 연구에 적합합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Plexin D1 synthetic peptide (coupled to carrier protein) corresponding to amino acids from the C-terminal region of human Plexin D1. This sequence is well conserved in rat and mouse Plexin D1, and has some homology to other Plexin family members. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2942978 |
Product Specific Information
The antibody detects 215 and 195 kDa bands corresponding to the apparent molecular mass of Plexin D1 variants in human umbilical vein endothelial cells.
Target Information
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla and endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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