Thermo Fisher Scientific H1FOO Polyclonal Antibody
H1FOO 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능하며 인간 시료 반응성. 고순도 항원 친화 크로마토그래피 정제, 35 kDa 단백질 검출에 적합.
- 카탈로그번호
- PA536111
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal of human Histone H1oo |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2553374 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of approximately 35 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Eukaryotic Histones are basic, water-soluble nuclear proteins forming hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn to form chromosomal fibers.
Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer consisting of two H2A–H2B dimers and two H3–H4 dimers that are nearly symmetrical in tertiary structure.
Over 80% of nucleosomes contain linker histone H1, derived from an intronless gene, which interacts with linker DNA between nucleosomes and mediates compaction into higher-order chromatin.
H1FOO (H1 histone family, member O, oocyte-specific), also known as OSH1, is a 346 amino acid oocyte-specific histone that localizes to both the nucleus and cytoplasm. It is expressed as multiple alternatively spliced isoforms and plays an important role in gene control during oogenesis and early embryogenesis, crucial for meiotic maturation of germinal vesicle-stage oocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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