Thermo Fisher Scientific DR6 Polyclonal Antibody
Human TNFRSF21/DR6 단백질을 인식하는 Rabbit Polyclonal Antibody. Western Blot 및 ELISA에 적합하며, 보존제가 없는 액상 형태로 제공. Protein A 및 항원 친화 크로마토그래피로 정제되어 고순도 확보. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TNFRSF21/DR6 protein (Met1–Leu350) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788328 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human TNFRSF21/DR6.
Target Information
DR6 (Death Receptor 6) is widely expressed in human tissues and cell lines. Its ligand has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand through death domain-containing receptors such as TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 have been identified. DR6, a newly cloned death domain-containing receptor in the TNFR family, interacts with the adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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