Thermo Fisher Scientific BRG1 Monoclonal Antibody (BRG-01)
BRG1 단백질의 C-말단 부위를 인식하는 단클론 항체로, Western blot에 적합합니다. Human 시료에 반응하며, Protein A로 정제된 액상 형태입니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 10 µg/mL
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BRG-01 |
| Immunogen | Bacterially produced GST-fused protein representing 242 C-terminal amino acids of human Brg1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152472 |
Product Specific Information
This antibody recognizes an epitope within the C-terminal part of human Brg1, a 205 kDa catalytic subunit of SWI2/SNF2-family chromatin-remodeling complexes.
Target Information
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair, and DNA replication.
Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cell differentiation, neurogenesis, and cell cycle regulation, and are absolutely necessary for mouse embryogenesis.
Brg1 is also involved in cell growth arrest, senescence, and tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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