Thermo Fisher Scientific CD4 Monoclonal Antibody (GK1.5), PE
마우스 CD4 단백질을 인식하는 단클론 항체로, PE로 결합되어 유세포분석(Flow Cytometry)에 적합합니다. Rat IgG2b 아이소타입이며, 액상 형태로 제공됩니다. 4°C 암조건 보관, 동결 금지. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Flow Cytometry (Flow) | 1–2 µg/mL | View 3 publications |
| Miscellaneous PubMed (Misc) | - | View 6 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GK1.5 |
| Immunogen | Mouse CTL clone V4 cells |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation/Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152678 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of mouse CD4 transmembrane glycoprotein (55 kDa).
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but may also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression can be observed in the thymus, lymph nodes, tonsils, spleen, and specific regions of the brain and gut. CD4 functions to initiate or enhance early T-cell activation through association with the T-cell receptor complex and protein tyrosine kinase Lck.
It may also mediate neuronal damage in infectious and immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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