Thermo Fisher Scientific CD4 Monoclonal Antibody (GK1.5), APC
Thermo Fisher Scientific의 CD4 Monoclonal Antibody (GK1.5), APC는 마우스 CD4 항원 인식용 Rat IgG2b 단클론 항체입니다. Flow Cytometry 및 IHC에 적합하며, APC 형광 표지(Ex/Em: 651/660 nm)를 제공합니다. 4°C에서 암소 보관하며, 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
- View 1 publication
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/mL
- View 2 publications
Miscellaneous PubMed (Misc)
- Tested Dilution: Not specified
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GK1.5 |
| Immunogen | Mouse CTL clone V4 cells |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152647 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of mouse CD4 transmembrane glycoprotein (55 kDa).
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed on T helper cells but may also be found on monocytes, macrophages, and dendritic cells. Tissue expression includes thymus, lymph nodes, tonsils, spleen, and specific regions of the brain and gut. CD4 participates in T-cell activation through association with the T-cell receptor complex and protein tyrosine kinase Lck, and may mediate neuronal damage in immune-related CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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