Thermo Fisher Scientific SPARC Recombinant Rabbit Monoclonal Antibody (PD00-57)
SPARC 단백질을 인식하는 토끼 단클론 항체로, IHC(P)에서 1:500~1:2,000 희석 사용 가능. HEK293 세포에서 발현된 재조합 항체이며, 인간 시료에 반응. 단백질 A로 정제된 액상 제품으로 장기 보관 시 -20°C 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:2,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PD00-57 |
| Immunogen | Synthetic peptide aa 18–303/303 (SPARC, UniProt ID: P09486-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_3093015 |
Product Specific Information
- Positive Control: Human malignant melanoma tissue, human glioma tissue
- Predicted Band Size: 35 kDa
- Subcellular Location: Secreted, extracellular space, extracellular matrix, basement membrane
Target Information
The SPARC gene encodes a cysteine-rich acidic matrix-associated protein. This protein is essential for bone collagen calcification and plays roles in extracellular matrix synthesis and cell shape modulation. It has been linked to both tumor suppression and metastasis due to its effects on cell morphology and invasion. Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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