Thermo Fisher Scientific Phospho-S6 Ribosomal Protein (Ser235, Ser236) Recombinant Rabbit Monoclonal Antibody (S6S235S236-R3A2)
Phospho-S6 Ribosomal Protein (Ser235/236) 인산화 상태를 검출하는 고특이성 재조합 토끼 단클론 항체. Western blot 및 Flow cytometry에 적합. Human 및 Mouse 반응성. Protein A/G 정제, PBS/glycerol 버퍼, -20°C 보관.
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- MA536931
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- pk
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Thermo Fisher Scientific Phospho-S6 Ribosomal Protein (Ser235, Ser236) Recombinant Rabbit Monoclonal Antibody (S6S235S236-R3A2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Flow Cytometry (Flow) | 1–1,000 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | S6S235S236-R3A2 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser235/236 of human phospho S6 Ribosomal Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol, 0.10% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896866 |
Additional Formats
Target Information
Ribosomes are organelles that catalyze protein synthesis, composed of a small 40S subunit and a large 60S subunit. These subunits include 4 RNA species and approximately 80 structurally distinct proteins. The encoded cytoplasmic ribosomal protein is part of the 40S subunit and belongs to the S6E family. It serves as a major substrate for protein kinases, with phosphorylation occurring on five C-terminal serine residues. Phosphorylation is induced by growth factors, tumor-promoting agents, and mitogens, while dephosphorylation occurs during growth arrest. This protein contributes to cell growth and proliferation regulation by selective translation of specific mRNA classes. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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