Thermo Fisher Scientific GSTM5 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive control: mouse brain
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase that belongs to the mu class, which functions in detoxification of electrophilic compounds including carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products by conjugation with glutathione.
Genes encoding the mu class enzymes are organized in a cluster on chromosome 1p13.3 and are highly polymorphic, influencing susceptibility to toxins and drug efficacy. Diversification has occurred in substrate-binding domains and tissue expression patterns to handle various foreign compounds.

⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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