Thermo Fisher Scientific HPD Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive control: HepG2
• Predicted reactivity: Mouse (90%), Rat (89%), Pig (88%), Bovine (92%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. Recently, a serine protease called Omi/HtrA2 has been identified, which is released from mitochondria upon induction of apoptosis. Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. Deregulated expression of Omi in the cytoplasm induces apoptosis, suggesting its role in the mitochondrial apoptotic pathway.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.