Thermo Fisher Scientific eIF4B Recombinant Rabbit Monoclonal Antibody (7H67L68)
Recombinant rabbit monoclonal antibody targeting human eIF4B. Validated for ICC/IF applications with 1:100 dilution. Offers high specificity, sensitivity, and lot-to-lot consistency. Suitable for research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7H67L68 |
| Immunogen | Protein corresponding to human eIF4B [aa88–aa178] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2734806 |
Product Specific Information
This antibody is predicted to react with Monkey, Horse, Pig, and Rat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin–free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to mRNA. It functions closely with eIF4F and eIF4A, binding near the 5′-terminal cap of mRNA in the presence of eIF4F and ATP. eIF4B promotes the ATPase activity and ATP-dependent RNA unwinding activity of both eIF4A and eIF4F.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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